With the deepening of chondroitin sulfate and the continuous development of science and technology, its application prospects in medicine, bioengineering and pharmaceutical fields will be more and more broad. Chondroitin sulfate is a class of sulfated glycosaminoglycan, widely distributed in the extracellular matrix and cell surface of animal tissues, with various pharmacological activities such as anti-inflammatory, immune regulation, cardiovascular, cerebrovascular protection, neuroprotection, antioxidant, cell adhesion regulation, and anti-tumor. In Europe, the United States, Japan and many other countries, chondroitin sulfate is mainly used as a health food or medicine, for the prevention and treatment of cardiovascular and cerebrovascular diseases, osteoarthritis, neuroprotection and so on.