The efficacy and function of bovine collagen peptide

This article will take a closer look at the benefits of bovine collagen peptides for skin, joint and bone health.

Bovine collagen peptides are a high-purity, low-molecular-weight collagen decomposition product extracted from bovine bones or hides. They have a variety of biological activities and have significant benefits for skin, joint and bone health. The following is a detailed discussion of their role in different health areas and the relevant research support:

Product Name Bovine Collagen peptide
CAS Number 9007-34-5
Origin Bovine hides, grass fed
Appearance White to off white Powder
Production process Enzymatic Hydrolysis extraction process
Protein Content ≥ 90% by Kjeldahl method
Solubility Instant and Quick Solubility into cold water
Molecular weight Around 1000 Dalton
Bioavailability High bioavailability
Flowability Good flowabilityq
Moisture content ≤8% (105°for 4 hours)
Application Skin care products, joint care products, snacks, sports nutrition products
Shelf Life 24 months from production date
Packing 20KG/BAG, 12MT/20' Container, 25MT/40' Container

Benefits for skin health

 

1.Improving skin elasticity and moisturizing: Bovine collagen peptides can be quickly absorbed by the human body and work in the skin. Studies have shown that supplementing with bovine collagen peptides can significantly improve the moisture content, elasticity and radiance of  the skin and reduce the appearance of wrinkles. For example, a randomized controlled trial (BECOME study) is evaluating the effects of bovine collagen supplements on indicators such as skin elasticity and moisturizing, and preliminary results show that it has a positive effect on improving skin health.

 

2.Antioxidant and anti-photoaging: Bovine collagen peptides have antioxidant properties, can scavenge free radicals, and reduce UV damage to the skin. Research by Japanese scholars has found that low-molecular-weight collagen hydrolysates can reduce UVA-induced skin tissue damage and DNA damage.

 

3.Promoting skin repair: Bovine collagen peptides can stimulate the synthesis of collagen in the skin and accelerate the repair process of damaged skin.

Bovine-collagen
Bovine-collagen-peptide-1

Benefits to joint health

 

1.Relieve joint pain and inflammation: Bovine collagen peptides can effectively remove oxygen free radicals produced in inflammatory reactions, protect joint cartilage, and relieve joint pain and inflammation. Studies have also shown that bovine collagen peptides can inhibit the production of inflammatory factors and relieve arthritis symptoms.

 

2.Promote cartilage repair and regeneration: Bovine collagen peptides can directly participate in the repair process of damaged articular cartilage, promote chondrocyte proliferation, stimulate cartilage matrix synthesis, and accelerate recovery after joint injury.

 

3.Improve joint range of motion: Supplementing with bovine collagen peptides can improve joint flexibility and range of motion and reduce joint stiffness.

Benefits to bone health 

 

1.Promote bone cell generation and bone increase: Bovine collagen peptides can promote the number of bone cells, increase bone density, and improve osteoporosis symptoms. Studies have found that bovine collagen peptides have a two-way regulatory effect on patients with osteoporosis, which can not only promote the generation of osteoblasts, but also increase the activity of osteoblasts, promote calcium binding and bone formation. 

 

2.Enhance bone strength and toughness: Bovine collagen peptides are an important component of bones. Supplementing with bovine collagen peptides can enhance bone strength and toughness and reduce the risk of fractures.

 

3.Auxiliary treatment of osteoporosis: In the treatment of osteoporosis, the combination of bovine collagen peptides and calcitonin can inhibit the decomposition of bone collagen better than calcitonin alone.

Bovine Chondroitin Sulfate

What is the specific mechanism of bovine collagen peptides in repairing articular cartilage?

 

The specific mechanism of bovine collagen peptides on articular cartilage repair mainly includes the following aspects:

 

1. Stimulate chondrocyte proliferation and synthesis

Bovine collagen peptides can stimulate the proliferation of chondrocytes and promote the synthesis of proteoglycans and collagen by chondrocytes. These components are the main components of cartilage tissue and can enhance the wear resistance of cartilage, thereby helping to relieve joint pain symptoms. In addition, bovine collagen peptides can accelerate the repair process of damaged cartilage and reduce inflammatory responses.

 

2. Provide essential amino acids

Bovine collagen peptides are rich in amino acids such as glycine, proline and hydroxyproline, which play an important role in maintaining and repairing cartilage tissue. These amino acids can provide chondrocytes with raw materials for synthesizing collagen and proteoglycans, thereby promoting the repair and regeneration of cartilage.

 

3. Lubricate joints

Bovine collagen peptides can increase the secretion of synovial fluid, improve the lubrication of joints, reduce friction between bones, and thus improve joint mobility. This lubrication helps to reduce joint wear and relieve joint pain.

 

4. Inhibit inflammatory response

Studies have shown that bovine collagen peptides can inhibit the production of proinflammatory cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α). By inhibiting these inflammatory factors, bovine collagen peptides can reduce joint inflammation and protect articular cartilage from further damage.

 

5. Promote calcium absorption

Bovine collagen peptides can bind to calcium to form chelates, thereby promoting calcium absorption and utilization. This effect is of great significance for strengthening bone strength and improving osteoporosis, and also helps repair and regenerate cartilage.

 

6. Activate osteogenic signaling pathways

Bovine collagen peptide-calcium chelates can activate osteogenic activity-related signaling pathways and promote related gene expression by activating calcium-sensitive receptors (CaSRs), increasing intracellular calcium ion concentrations. This mechanism not only helps the formation and repair of bones, but also plays a positive role in the repair of articular cartilage.

 

Clinical application and research support

 

Multiple studies support the role of bovine collagen peptides in articular cartilage repair. For example, a study published in the< International Journal of Orthopaedics> pointed out that after taking bovine collagen peptides for 8 consecutive weeks, patients reported significantly reduced knee pain and significantly improved joint flexibility. Another study found that long-term use of bovine collagen peptides can effectively slow the rate of joint space narrowing and delay the progression of the disease.


Post time: Feb-20-2025